The uremic syndrome: Therapeutic-evaluative discordance

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Biochemical definition of the uremic syndrome and possible therapeutic implications.

Renal failure is characterized by the progressive decline in the capacity of the kidneys to eliminate toxic solutes. In parallel, the “uremic syndrome” is depicted by a functional disturbance of enzymes, organelles, cells, and organs. This leads to an overall malaise that ultimately ends in coma and death unless artificial kidney treatment (dialysis) is started (1). The current conception of di...

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접수 : 2007년 8월 23일, 승인 : 2007년 9월 13일 책임저자: 박혜원, 포천중문의대 소아과학교실 Correspondence: Hye Won Park, M.D. Tel : 031)780-5230 Fax : 031)780-5239 E-mail : [email protected] 하 등을 특징으로 하는 드문 질환으로 영아나 어린 소아의 급성 신부전의 가장 흔한 원인이다 1, 2) . 미세혈관병증 용혈성 빈혈의 성상은 파편이 된 적혈구(schistocytes)가 말초혈액 도말 검사에 서 관찰되고 혈청 lactate dehydrogenase(LDH), 유리 혈색소와 망상 적혈구가 증가하며, 대개의 경우 혈소판 수치는 60,000/ mm 3 이하로 감소한다 1, 3) . 임상 증상과 예후...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2003

ISSN: 0085-2538

DOI: 10.1046/j.1523-1755.63.s84.29.x