The uremic syndrome: Therapeutic-evaluative discordance
نویسندگان
چکیده
منابع مشابه
Biochemical definition of the uremic syndrome and possible therapeutic implications.
Renal failure is characterized by the progressive decline in the capacity of the kidneys to eliminate toxic solutes. In parallel, the “uremic syndrome” is depicted by a functional disturbance of enzymes, organelles, cells, and organs. This leads to an overall malaise that ultimately ends in coma and death unless artificial kidney treatment (dialysis) is started (1). The current conception of di...
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Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease characterized by complement overactivation. Inherited defects in complement genes and acquired autoantibodies against complement regulatory proteins have been described. Incomplete penetrance of mutations in all predisposing genes is r...
متن کاملHemolytic Uremic Syndrome
below), the emphasis for differentiating HUS from TTP has shifted from the pattern of clinical involvement to the presence or absence of the enzyme deficiency. It is now suggested that the diagnosis of TTP should be used to describe only those patients who have this enzyme deficiency; while patients without the enzyme deficiency should be labeled as suffering from HUS.4 ETIOLOGY AND PATHOGENESI...
متن کاملHemolytic uremic syndrome.
CONTEXT Hemolytic uremic syndrome (HUS) is a severe acute disease, sometimes with long-term sequelae. The diarrhoea-unrelated forms are particularly associated with a poor prognosis. The aim of this paper is to review current evidence regarding etiology and management, and explore methods by which the outcome may be optimized. EVIDENCE ACQUISITION An internet search of Medline, Medscape, MDCo...
متن کاملHemolytic uremic syndrome
접수 : 2007년 8월 23일, 승인 : 2007년 9월 13일 책임저자: 박혜원, 포천중문의대 소아과학교실 Correspondence: Hye Won Park, M.D. Tel : 031)780-5230 Fax : 031)780-5239 E-mail : [email protected] 하 등을 특징으로 하는 드문 질환으로 영아나 어린 소아의 급성 신부전의 가장 흔한 원인이다 1, 2) . 미세혈관병증 용혈성 빈혈의 성상은 파편이 된 적혈구(schistocytes)가 말초혈액 도말 검사에 서 관찰되고 혈청 lactate dehydrogenase(LDH), 유리 혈색소와 망상 적혈구가 증가하며, 대개의 경우 혈소판 수치는 60,000/ mm 3 이하로 감소한다 1, 3) . 임상 증상과 예후...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2003
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.63.s84.29.x